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Effect of Deep Optic Nerve Head Morphology on Lamina Cribrosa and Peripapillary Scleral Configurations in Healthy Eyes.


ABSTRACT:

Purpose

The purpose of this study was to investigate the relationship among deep optic nerve head (ONH), lamina cribrosa (LC), and peripapillary sclera (pSc) configurations in healthy eyes.

Methods

This prospective cross-sectional study included 205 healthy eyes of 141 subjects. Multivariable linear mixed models identified factors associated with LC curvature index, prelaminar thickness (PLT), pSc angle, and LC depth (LCD). Explanatory variables included age, gender, intraocular pressure, axial length (AXL), visual field sensitivity, disc area, disc ovality, disc torsion, Bruch's membrane opening (BMO)-minimum rim width (MRW), BMO and anterior scleral canal opening (ASCO) area, peripapillary zone area with and without Bruch's membrane (PPZ+BM/-BM), and peripapillary choroida

SUBMITTER: Enomoto N 

PROVIDER: S-EPMC12315936 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature