Biochemical neuroplasticity in the cerebellum after physical exercise: Systematic review and meta-analysis.

ABSTRACT:

Background

Neuroplasticity is the central nervous system's (CNS) capacity to adapt to injuries or environmental changes. Biochemical neuroplasticity is one such adaptation that may occur in response to physical exercise (PE). This systematic review and meta-analysis aimed to evaluate the effects of PE on cerebellar biochemical neuroplasticity.

Methods

Following the PICO strategy, this review included in vivo studies with small rodents (Population) subjected to well-defined PE protocols (Intervention) and compared to non-exercised controls (Comparator) to assess cerebellar biochemical alterations (Outcome). Studies published between January 1976 and July 2024 without language restrictions were searched in PubMed, Scopus, Web of Science, and Cochrane Central databases. Data we

SUBMITTER: Correa MG 

PROVIDER: S-EPMC12316286 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature