Temporal trends in glucocorticoids and hydroxychloroquine for treatment of systemic lupus erythematosus in Sweden.

ABSTRACT:

Objectives

It is unknown to what extent updated treatment recommendations regarding glucocorticoids (GC) and hydroxychloroquine (HCQ) for patients with systemic lupus erythematosus (SLE) have been incorporated into clinical practice. Based on filled dispensations we examined treatment patterns the first 5 years after SLE diagnosis in Sweden, trends over time and relationship to patient characteristics.

Methods

A cohort of patients with newly diagnosed SLE between 2005 and 2021 with information on drug dispensations, hospitalizations, specialized outpatient visits and patient characteristics were identified through a linkage of Swedish population registers (n = 3891, 83% females, mean age 48.8). Treatment patterns, including accumulated exposure to GC and HCQ and combinations

SUBMITTER: Dominicus A 

PROVIDER: S-EPMC12316358 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature