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ABSTRACT: Objectives
Sleep disturbance is a key symptom of fibromyalgia and a risk factor for chronic widespread pain. This systematic review and meta-analysis aims to assess the effectiveness of pharmacological treatments and cognitive behavioural therapy (CBT) in improving sleep quality in fibromyalgia patients.Methods
A systematic search of PubMed, MEDLINE, Embase, Cochrane CENTRAL and CINAHL was conducted for randomized controlled trials (RCTs) published up to April 2023. Studies assessing pharmacological or CBT interventions with sleep-related outcomes were included. Data were extracted, and meta-analyses were performed where applicable. Study quality and bias were evaluated using the Cochrane Risk of Bias tool.Results
Forty-seven RCTs, including 11 094 participants, wer
SUBMITTER: Pathak A
PROVIDER: S-EPMC12316380 | biostudies-literature | 2025 Aug
REPOSITORIES: biostudies-literature