Effectiveness and equity of vaccination strategies against Rift Valley fever in a heterogeneous landscape.

ABSTRACT: Spatio-temporal variations in environmental and socio-agricultural factors create heterogeneity in livestock disease transmission risk, raising challenges in identifying populations most at risk and how this risk changes over time. Consequently, effective vaccination strategies require careful planning to achieve optimal or equitable outcomes across regions. We developed a metapopulation model for Rift Valley fever transmission in livestock across the Comoros archipelago which incorporates livestock vaccination in addition to heterogeneity in viral transmission rates and animal movements. We used the model to evaluate three vaccine allocation strategies-proportional allocation, optimal allocation for maximising total infections averted across the archipelago, and optimal allocation for mor

SUBMITTER: Tennant WSD 

PROVIDER: S-EPMC12316399 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature