The cystic fibrosis pathogen <i>Achromobacter xylosoxidans</i> inhibits biofilm formation of <i>Pseudomonas aeruginosa</i>.

ABSTRACT: Background. Achromobacter xylosoxidans and Pseudomonas aeruginosa are two pathogens that cause persistent airway infections in individuals with cystic fibrosis (CF). The persistence of P. aeruginosa is partly due to a high capacity to form biofilms and the ability to exert antagonism against other bacteria. Loss of microbial diversity in conjunction with chronic P. aeruginosa colonization is strongly correlated with low lung function in CF. A. xylosoxidans and P. aeruginosa are frequently co-isolated in CF airway cultures. This study aims to investigate the reciprocal effects on growth inhibition and biofilm formation between P. aeruginosa and A. xylosoxidans in vitro.Method. Six isolates of A. xylosoxidans, isola

SUBMITTER: Sahl C 

PROVIDER: S-EPMC12316436 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature