Urinary Levels of Endocrine-Disrupting Chemicals and Breast Density in Young Women.

ABSTRACT:

Background

Endocrine-disrupting chemicals (EDC) found in many household and personal care products have hormonal properties and effects on the mammary gland. It is unclear whether urinary concentrations of EDCs are associated with higher percent breast density, a major risk factor of breast cancer.

Methods

We conducted a cross-sectional study of 97 college-aged women. We quantified individual levels of bisphenol A, bisphenol S, bisphenol F, triclosan, triclocarban, 3-benzophenone, seven phthalate metabolites, four parabens, and two other phenols in three 24-hour urine samples combined into a single pooled sample. Each woman had non-enhanced MRI to assess percent breast density. Associations between estimated concentrations of individual EDCs and percent breast density were a

SUBMITTER: Carroll JE 

PROVIDER: S-EPMC12316558 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature