Food Insecurity and Clinical Biomarkers of Inflammation among Cancer Survivors in the All of Us Research Program.

ABSTRACT:

Background

Food insecurity is associated with a 40% increase in the prevalence of chronic conditions, including cancer. Stress-evoked inflammation is a hypothesized mechanism driving these associations. This study tested the association between food insecurity and inflammation in cancer survivors.

Methods

Our sample included individuals with a history of lung, breast, prostate, and colorectal cancers from the All of Us Research Program. Food insecurity was measured using validated questions, and inflammatory biomarkers were obtained from electronic health records (EHR). Our primary analysis tested the association between food insecurity and C-reactive protein (CRP; n = 413) using multivariable regression models, controlling for sociodemographics and current cancer treatment.

SUBMITTER: Byrne CA 

PROVIDER: S-EPMC12316563 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature