Diagnostic evaluation to identify infection-attributable stillbirth.

ABSTRACT:

Objective

To characterize stillbirth evaluations, including the frequency and yield of investigations for infections causing stillbirth.

Study design

Retrospective cohort of stillbirths at three university-affiliated perinatal centers from 2017 to 2022. The primary outcome was adherence to American College of Obstetrics and Gynecology core stillbirth evaluation recommendations (placental pathology, fetal autopsy, and fetal genetic testing). We further characterized the prevalence and yield of specific testing to evaluate for infection-attributable stillbirth etiologies.

Results

The cohort included 399 stillbirths. Placental pathology was performed in 387 cases (97.0%), fetal genetic testing in 163 (40.9%), and fetal autopsy in 126 (31.6%). Fetal bacterial cultures wer

SUBMITTER: Coggins SA 

PROVIDER: S-EPMC12316590 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature