Repeatability and prognostic value of radiomic features: a study in esophageal cancer and nasopharyngeal carcinoma.

ABSTRACT:

Objectives

To investigate whether radiomic features (RFs) repeatability and their prognostic value are study-specific.

Materials and methods

This retrospective study included 234 esophageal cancer (EC) patients (contrast-enhanced computed tomography (CECT) and fluorine-18 fluorodeoxyglucose positron emission tomography (PET)), and 525 nasopharyngeal carcinoma (NPC) patients (CECT). Tumor, peritumor, and lymph node regions were defined as regions of interest. RF repeatability was assessed via perturbation analysis using intraclass correlation coefficients (ICC), with consistency and differences across cancer types, pathological regions, and modalities evaluated. The independent prognostic features common to both EC and NPC were screened from highly repeatable features using C

SUBMITTER: Gong J 

PROVIDER: S-EPMC12316612 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature