Fabrication and characterizations of 3D printed GelMA-Gel/bioactive glass scaffolds containing cerium for bone damage repair.

ABSTRACT: Gelatin methacryloyl (GelMA) and bioactive glasses (BGs) have attracted considerable scientific interest as scaffold materialsin bone tissue engineering, particularly for their structural applications in bone repair procedures. Cerium (Ce) can be incorporated into BGs, demonstrating beneficial effects on osteogenesis and regenerative processes. In this study, we fabricated GelMA-Gel scaffolds using a 3D printing method and evaluated the impact of BG and BG/Ce inclusion through in vitro and in vivo assessments. Scanning electron microscopy images revealed an interconnected porous structure within the scaffolds. The incorporation of Ce appeared to enhance the mechanical properties of the scaffolds. Additionally, the inclusion of Ce did not induce cytotoxicity and positively influenced the vi

SUBMITTER: Jalilinejad N 

PROVIDER: S-EPMC12316854 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature