Padua Score and D-dimer for Pulmonary Embolism Exclusion in the Elderly.

ABSTRACT:

Purpose

This study was aimed at identifying biomarkers that could help exclude pulmonary embolism (PE) in patients aged 65 years and older, considering age-related challenges such as atypical clinical presentations and the presence of comorbidities.

Methods

This single-center cohort study retrospectively collected data on 28 potential markers from patients aged 65 years and older who underwent computed tomography scans for PE diagnosis in emergency or internal wards over a 2.5-year period.

Results

The study included 157 patients after exclusions, with 35 diagnosed with PE. Patients with PE exhibited higher D-dimer levels, lower platelet counts, and higher Padua scores. Six markers were selected based on likelihood ratio, each with an area under the curve above 0.7 and

SUBMITTER: Cohen R 

PROVIDER: S-EPMC12316886 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature