Silver coated porous silicon microarray SERS platform for detecting aflatoxin B1 fumonisin B1 and ochratoxin A.

ABSTRACT: Toxigenic mold contamination in food and agricultural commodities affects a quarter of the world's crops with massive economic losses and consequential health risks. Herein, we present a newly developed nanostructured microarray based on silver-coated porous silicon (Ag-pSi) used as a surface-enhanced Raman scattering (SERS) transducer. The internal porous void and pore morphology were optimized to amplify the SERS effect while achieving an enhancement factor of 1.75 × 10⁷. The optimal structural features were used to analyze three target mycotoxins simultaneously using a portable Raman device. The optical output was inversely proportional to the analyte concentration upon selective biorecognition by the anti-target mycotoxin aptamer-modified scaffold. The Ag-pSi SERS substrate

SUBMITTER: Singh RK 

PROVIDER: S-EPMC12317008 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature