Reference library for suspect screening of environmental toxicants using ion mobility spectrometry-mass spectrometry.

ABSTRACT: Due to the potential health risks related to chemical exposure, rapidly assessing xenobiotic molecules in the environment and those already in the body is imperative. Targeted analytical methods coupling either gas or liquid chromatography with mass spectrometry (GC-MS or LC-MS) are commonly utilized in current exposure assessments. While these methods are accepted as the gold standard for exposure analyses, they often require multiple sample preparation steps and analysis times > 30 min. These limitations have resulted in an evolving interest in using ion mobility spectrometry and MS (IMS-MS), either with or without chromatography, to improve throughput and annotation confidence. To increase IMS-MS information availability for exposure studies, here we utilized drift tube IMS-MS to evalua

SUBMITTER: Teri D 

PROVIDER: S-EPMC12317010 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature