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The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium.


ABSTRACT: The complete genome of the green-sulfur eubacterium Chlorobium tepidum TLS was determined to be a single circular chromosome of 2,154,946 bp. This represents the first genome sequence from the phylum Chlorobia, whose members perform anoxygenic photosynthesis by the reductive tricarboxylic acid cycle. Genome comparisons have identified genes in C. tepidum that are highly conserved among photosynthetic species. Many of these have no assigned function and may play novel roles in photosynthesis or photobiology. Phylogenomic analysis reveals likely duplications of genes involved in biosynthetic pathways for photosynthesis and the metabolism of sulfur and nitrogen as well as strong similarities between metabolic processes in C. tepidum and many Archaeal species.

SUBMITTER: Eisen JA 

PROVIDER: S-EPMC123171 | biostudies-literature | 2002 Jul

REPOSITORIES: biostudies-literature

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The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium.

Eisen Jonathan A JA   Nelson Karen E KE   Paulsen Ian T IT   Heidelberg John F JF   Wu Martin M   Dodson Robert J RJ   Deboy Robert R   Gwinn Michelle L ML   Nelson William C WC   Haft Daniel H DH   Hickey Erin K EK   Peterson Jeremy D JD   Durkin A Scott AS   Kolonay James L JL   Yang Fan F   Holt Ingeborg I   Umayam Lowell A LA   Mason Tanya T   Brenner Michael M   Shea Terrance P TP   Parksey Debbie D   Nierman William C WC   Feldblyum Tamara V TV   Hansen Cheryl L CL   Craven M Brook MB   Radune Diana D   Vamathevan Jessica J   Khouri Hoda H   White Owen O   Gruber Tanja M TM   Ketchum Karen A KA   Venter J Craig JC   Tettelin Hervé H   Bryant Donald A DA   Fraser Claire M CM  

Proceedings of the National Academy of Sciences of the United States of America 20020701 14


The complete genome of the green-sulfur eubacterium Chlorobium tepidum TLS was determined to be a single circular chromosome of 2,154,946 bp. This represents the first genome sequence from the phylum Chlorobia, whose members perform anoxygenic photosynthesis by the reductive tricarboxylic acid cycle. Genome comparisons have identified genes in C. tepidum that are highly conserved among photosynthetic species. Many of these have no assigned function and may play novel roles in photosynthesis or p  ...[more]

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