Perinatal risk assessment in pregnancies complicated by early-onset fetal growth restriction: development and internal validation of a prediction model for composite adverse perinatal outcome.

ABSTRACT:

Objective

Early-onset fetal growth restriction (FGR) frequently requires iatrogenic preterm delivery to prevent stillbirth or the sequelae of hypoxia. A prediction model for adverse perinatal outcome could aid clinical decision-making and parental counseling. However, an adequate externally validated model, including predictors that are readily available for this purpose, is currently lacking. The aim of the present study was to develop a prediction model for composite adverse perinatal outcome (CAPO) to be used at the time of hospital admission for fetal monitoring in early-onset FGR.

Methods

A model was developed to predict CAPOs (defined as one or more of the following: perinatal or in-hospital mortality, necrotizing enterocolitis ≥ Stage IIA, moderate or severe bronchopu

SUBMITTER: van de Meent M 

PROVIDER: S-EPMC12317299 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature