External validation of QUiPP App in three independent European cohorts of symptomatic women.

ABSTRACT:

Objective

To validate externally the QUantitative Innovation in Predicting Preterm birth (QUiPP) App v.2 for the prediction of spontaneous preterm birth (sPTB) in symptomatic women attending tertiary care in Europe.

Methods

The QUiPP App v.2 was validated in three independent datasets: a prospective European multicenter cohort across five countries (n = 452), a retrospective single-center cohort in The Netherlands (n = 581) and a retrospective single-center cohort in Belgium (n = 399). The cohorts consisted of pregnant women between 23 and 34 weeks' gestation with symptoms of threatened preterm birth attending a tertiary care hospital between 2012 and 2023. We calculated risk estimates using the QUiPP App v.2 by inputting quantitative fetal fibronectin (qfFN) and/or cervical

SUBMITTER: Fischer AM 

PROVIDER: S-EPMC12317302 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature