Association of Triglyceride-Glucose Body Mass Index with Target Organ Damage in Essential Hypertension: A Retrospective Cohort Study.

ABSTRACT: The triglyceride-glucose body mass index (TyG-BMI) is an emerging composite metabolic indicator in cardiovascular research. However, the link between TyG-BMI and target organ damage (TOD) in essential hypertension (EH) remains uncertain. This study investigated the association between TyG-BMI and TOD in patients with EH. We conducted a retrospective cohort study involving 493 individuals with EH. Participants were divided at the cohort-specific median into high and low TyG-BMI groups. Over a median follow-up of 23 months, 191 participants experienced TOD. Kaplan-Meier curves showed a significantly higher cumulative incidence of TOD in the high TyG-BMI group than in the low TyG-BMI group (p < 0.05). In multivariable logistic regression, TyG-BMI remained an independent correlate of TOD (adju

SUBMITTER: Huang X 

PROVIDER: S-EPMC12317321 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature