Initiation of Antiseizure Medications in Patients With Brain Abscess.

ABSTRACT:

Importance

Epilepsy is a common complication of brain abscess. However, the effectiveness of antiseizure medications (ASMs) in preventing epilepsy in brain abscess survivors is unknown.

Objective

To assess whether the initiation of ASMs is associated with a reduced risk of epilepsy.

Design, setting, and participants

This retrospective cohort study conducted a target trial emulation using US commercial insurance claims data from October 1, 2016, to June 30, 2022, and followed up patients for 180 days. The study population was restricted to those with a diagnosis of brain abscess using International Statistical Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes associated with an acute care visit. Only patients aged 18 years or older at

SUBMITTER: Nielsen VM 

PROVIDER: S-EPMC12317356 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature