Relationship between adverse childhood experiences and musculoskeletal pain: the mediating effect of depressive symptoms.

ABSTRACT:

Background

Adverse Childhood Experiences (ACEs) are linked to long-term health impacts, including musculoskeletal pain (MSP). However, the role of depressive symptoms (DS) as a mediator in this relationship is not well understood. This study examines the role of DS as a mediator in this relationship among middle-aged and older Chinese adults.

Methods

Utilizing data from 11,905 participants in the China Health and Retirement Longitudinal Study (CHARLS). ACEs were assessed using 12 indicators, MSP was determined based on reported pain locations (spine, upper limbs, and lower limbs), and DS were measured using the 10-item Center for Epidemiological Research Depression Scale (CESD-10). Logistic regression was used to evaluate the associations between ACEs and MSP, DS. Mediation

SUBMITTER: Jin Y 

PROVIDER: S-EPMC12317554 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature