Clinical profiles and health-related quality of life changes after treatment in advanced colorectal cancer patients: a nationwide study in China.

ABSTRACT:

Background

Colorectal cancer (CRC) is prevalent in China, but many features of CRC patients remain to be better characterized. We aimed to describe the characteristics of clinical epidemiology in CRC patients in China and to evaluate the changes in health-related quality of life (HRQOL) before and after treatment.

Methods

A hospital-based survey was conducted among CRC patients from 2020 to 2021, covering 14 cities in China. Data on demographic and clinical characteristics, disease knowledge, medical service utilization, medical expenditure, and HRQOL before and after treatment were surveyed. The multivariable regressions and structural equation model (SEM) were used to assess the association between characteristics and HRQOL.

Results

In the survey of 4589 patients, n

SUBMITTER: Liu H 

PROVIDER: S-EPMC12317623 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature