Predonation Prescription Opioid Use: A Novel Risk Factor for Readmission After Living Kidney Donation.

ABSTRACT: Implications of opioid use in living kidney donors for key outcomes, including readmission rates after nephrectomy, are unknown. We integrated Scientific Registry of Transplant Recipients data with records from a nationwide pharmacy claims warehouse and administrative records from an academic hospital consortium to quantify predonation prescription opioid use and postdonation readmission events. Associations of predonation opioid use (adjusted odds ratio [aOR]) in the year before donation and other baseline clinical, procedural, and center factors with readmission within 90 days postdonation were examined by using multivariate logistic regression. Among 14 959 living donors, 11.3% filled one or more opioid prescriptions in the year before donation. Donors with the highest level of predonat

SUBMITTER: Lentine KL 

PROVIDER: S-EPMC12317785 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature