Effect of Pharmacological Treatment on Exercise-Induced Bronchoconstriction and Allergic Inflammatory Response in Endurance Athletes.

ABSTRACT:

Background

Endurance athletes (EA) with lung disease and allergic inflammation have worse performance.

Purpose

To examine whether pharmacological treatment can reduce airway disorders such as exercise-induced bronchoconstriction (EIB) and allergic inflammatory response (AIR) in EA.

Study design

Prospective, controlled clinical trial.

Methods

EA who were marathon runners underwent eucapnic voluntary hyperventilation (EVH) for screening assessment. EA who fulfilled the criteria for an EIB+ after an EVH were included in the treatment group (EIB+; n=13), and those who did not were included in the control group (CON; n=18). The athletes were assessed before and 30 days after the intervention. Outcomes included cardiopulmonary exercise testing, lung function, allergi

SUBMITTER: da Silva RA 

PROVIDER: S-EPMC12317798 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature