Outcomes After Resection of Adenocarcinoma of the Gastric Cardia by Surgical Approach.

ABSTRACT:

Background

Total gastrectomy and esophagectomy are commonly used surgical approaches for cardia gastric adenocarcinoma (GA) resection. However, the preferred approach remains unclear. The objectives of this study were to identify predictors of receipt of surgical approach type and compare surgical approach outcomes.

Patients and methods

Patients with stage IB-IIIC cardia GA from 2004 to 2017 were identified within the National Cancer Database. Patients were compared on the basis of receipt of total gastrectomy versus partial gastrectomy with esophagectomy. Predictors of receiving esophagectomy were identified using multivariable logistic regression. Predictors associated with overall survival (OS) were assessed using a multivariable Cox proportional hazards model.

Results

SUBMITTER: Bates KR 

PROVIDER: S-EPMC12317889 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature