Optimizing Extracellular Products from Vibrio proteolyticus for Their Use as Postbiotics in Aquaculture.

ABSTRACT: Vibrio proteolyticus DCF12.2 has demonstrated its ability to be used as a probiotic for fish species. This study investigates how different culture conditions influence the activity of its extracellular products (ECPs) in aquaculture, focusing on enzymatic and antibacterial activity, cytotoxicity, biofilm modulation, short-chain fatty acid (SCFA) profiles, and effects on Photobacterium damselae subsp. piscicida virulence. Enzymatic assays showed a variety of hydrolytic activities, including amylase, caseinase, and collagenase, which can enhance digestion and nutrient absorption in fish. Antibacterial assays revealed that ECPs from V. proteolyticus grown in an experimental aquafeed and a partial replacement of that aquafeed by 25% of a blend of microalgae inhibited P. damselae subsp. piscic

SUBMITTER: Garcia-Marquez J 

PROVIDER: S-EPMC12317916 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature