Gibberellin-deactivating GA2OX enzymes act as a hub for auxin-gibberellin cross talk in <i>Arabidopsis thaliana</i> root growth regulation.

ABSTRACT: Plant bodies are built from immobile cells, making the regulation of cell expansion essential for growth, development, and adaptation. In roots, cell elongation executes the movement of the root tips through the soil. This process is tightly controlled by numerous signaling pathways. Among these, gibberellin and auxin signaling stand out for their contrasting effects on root growth, interacting through complex cross talk at multiple regulatory levels. Here, we reveal the molecular basis of the auxin-gibberellin cross talk in the model plant Arabidopsis thaliana. We show that the auxin signaling pathway steers the expression of GIBBERELLIN 2-OXIDASES (GA2OXs), key gibberellin-deactivating enzymes in the root elongation zone (EZ). GA2OXs are negative regulators of root cell elo

SUBMITTER: Kubalova M 

PROVIDER: S-EPMC12318176 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature