ATP synthesis driven by atmospheric hydrogen concentrations.

ABSTRACT: All cells require a continuous supply of the universal energy currency, adenosine triphosphate (ATP), to drive countless cellular reactions. The universally conserved F₁F_o-ATP synthase regenerates ATP from ADP and P_i by harnessing a transmembrane electrochemical proton gradient (pmf). Bacteria have evolved diverse pmf-forming strategies using light, organic, and inorganic energy sources. Recently, we proposed that many bacteria survive using atmospheric trace gases to produce ATP when limited for other energy sources. However, direct evidence that atmospheric energy sources are sufficient to generate pmf or drive ATP synthesis is still lacking. Here, we show that the membrane-associated hydrogen:quinone oxidoreductase Huc from Mycoba

SUBMITTER: Soom S 

PROVIDER: S-EPMC12318194 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature