Molecular mechanism of nano-vitamin A-mediated regulation of intramuscular fat deposition involving noncoding RNAs in pigs.

ABSTRACT:

Background

Intramuscular fat content is a key factor influencing pork quality. Previous studies by our group found that intramuscular injection of Nano VA into newborn piglets significantly increased Intramuscular fat content and improved pork quality. However, the regulatory mechanisms of noncoding RNAs in Intramuscular fat deposition remain unclear.

Results

To elucidate the mechanisms by which Nano VA affects pork quality via noncoding RNAs, whole transcriptome sequencing was performed on the longissimus dorsi muscle from control and Nano VA treated groups. A total of 90 differentially expressed circRNAs (DECs), 805 differentially expressed lncRNAs (DELs), and 58 differentially expressed miRNAs (DEmiRs) were screened between the two groups. Among these, 53 DECs were upregu

SUBMITTER: Li M 

PROVIDER: S-EPMC12318395 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature