Y-Chromosome Genetic Characterization Supports the Establishment of Calving Centered Protected Areas for Tibetan Antelope Conservation.

ABSTRACT: Tibetan antelope (Pantholops hodgsonii), the flagship species of the Qinghai-Tibet Plateau, is renowned for its hardiness and resistance to low oxygen. Most of the previous studies focused on mitochondria and autosomes, with fewer studies related to the Y-chromosome. Therefore, in this study, we analyzed the Y-chromosome genetic diversity, population structure, and historical dynamics of Tibetan antelope populations using 26 Y-SNP loci and 5 Y-SSR polymorphic loci. Our results revealed a nucleotide diversity of 0.00092 ± 0.00002 and a haplotype diversity of 0.843 ± 0.029 based on 26 Y-SNPs from 14 sequences, with a total DNA sequence length of 10,675 bp. Genotyping of 123 Tibetan antelope male samples with 5 Y-SSR loci indicated a mean observed number of alleles of 6.600, an effecti

SUBMITTER: Wang S 

PROVIDER: S-EPMC12318635 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature