Association between the dietary index for gut microbiota and metabolic syndrome: the mediating role of the dietary inflammatory index.

ABSTRACT:

Background

Metabolic syndrome (MetS) poses a huge global public health challenge. The dietary index for gut microbiota (DI-GM) measures the influence of diets on the microbiome, but its link with the odds of MetS is elusive. This paper examined the link between DI-GM and MetS and investigated the mediating role of the dietary inflammatory index (DII).

Methods

Data were sourced from the 2007-2018 NHANES for adults diagnosed with MetS. A total of 20,999 participants were included in the analysis. Dietary data were recorded via two 24-h dietary recalls, from which DI-GM and DII were calculated. Multivariate weighted logistic regression and restricted cubic spline (RCS) analyses were leveraged to assess the link between DI-GM and MetS. Mediation analysis was implemented to deter

SUBMITTER: Han YN 

PROVIDER: S-EPMC12318735 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature