Prevalence and Clinical Characteristics of Severe Asthma With Fungal Sensitization in Korea.

ABSTRACT:

Purpose

Severe asthma with fungal sensitization (SAFS) is associated with life-threatening exacerbation and severe airflow limitation. We aimed to investigate the prevalence of fungal sensitization in asthma and clinical characteristics of SAFS.

Methods

This study analyzed data from the Cohort for Reality and Evolution of Adult Asthma in Korea and the Korean Severe Asthma Registry cohorts. Study subjects were classified based on fungal sensitization and asthma severity. Clinical characteristics of patients with severe asthma were compared according to fungal sensitization status.

Results

The rate of skin test positivity to fungi was 14.1% and 7.1% in severe asthma (n = 270) and non-severe asthma (n = 2,605). Patients with SAFS were diagnosed with asthma earlier than t

SUBMITTER: Rhyou HI 

PROVIDER: S-EPMC12318808 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature