Trends in Contact Allergy to Preservatives From 2014 to 2023: Benzisothiazolinone on the Rise.

ABSTRACT:

Background

Skin sensitising preservatives are commonly used in consumer and industrial products. The widespread use of preservatives has led to recurrent epidemics of contact allergy.

Objectives

To investigate temporal trends of contact allergy to preservatives from 2014 to 2023.

Materials and methods

Patients consecutively patch tested with preservatives from the European baseline series and the supplementary baseline series at Gentofte hospital from 2014 to 2023 were included.

Results

The study population included 6435 patients. Contact allergy to benzisothiazolinone (BIT) increased significantly from ≤ 0.3% in 2014 to 5.0% in 2023. Painters and machine operators, and assemblers were most often sensitised to BIT, and detergents and paints were the most common

SUBMITTER: Sogaard R 

PROVIDER: S-EPMC12318914 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature