Enhancing the antibacterial ability of <i>Ligilactobacillus salivarius</i> through ARTP mutagenesis breeding: an effective strategy to improve its probiotic properties.

ABSTRACT:

Introduction

Ligilactobacillus salivarius (L. salivarius), a well-characterized probiotic species with established safety and functional efficacy, has been widely applied in poultry production for decades. Its probiotic attributes primarily encompass inhibiting pathogenic bacterial proliferation, regulating host intestinal microbiota, and modulating immune responses to enhance animal health. Given the substantial variability in biological and probiotic characteristics among different L. salivarius strains, identifying optimal strains with enhanced probiotic efficacy typically requires extensive in vivo evaluations.

Methods

In this study, we employed atmospheric and room temperature plasma (ARTP) mutagenesis to improve the antibacterial activity of

SUBMITTER: Zhou H 

PROVIDER: S-EPMC12318943 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature