A clinical prediction model for blood pressure changes after renal denervation in patients with resistant hypertension.

ABSTRACT:

Objective

To develop clinical prediction models to estimate blood pressure changes in hypertensive patients undergoing renal denervation (RDN).

Methods

This single-center, prospective interventional study enrolled 70 hypertensive patients undergoing RDN between July 2022 and December 2023, with clinical data collected systematically before and after the procedure. Variable selection for modeling was performed through a rigorous process incorporating univariate analysis and clinical relevance assessment. Subsequently, two distinct clinical prediction models were developed and subjected to comparative evaluation. The primary outcomes were the absolute changes in systolic blood pressure (SBP) and diastolic blood pressure (DBP) at 6 months after RDN.

Results

In both Ordin

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12319003 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature