Sarcopenia defined by multidimensional factors and its prognostic role in heart failure: a systematic review and meta-analysis.

ABSTRACT:

Objective

To perform a systematic review and meta-analysis evaluating the impact of sarcopenia-defined by reductions in muscle mass, strength, and/or function-on clinical outcomes in patients with heart failure (HF), thereby informing more effective management strategies.

Methods

A comprehensive literature search was conducted through 14 February 2025, using PubMed, Embase, Cochrane Library, and CNKI to identify prospective and retrospective cohort studies involving HF patients diagnosed with sarcopenia based on Asian Working Group for Sarcopenia (AWGS), European Working Group on Sarcopenia in Older People (EWGSOP2), or Ishii criteria. Data extraction was performed using standardized forms, and study quality was assessed using the Newcastle-Ottawa Scale (NOS). Meta-analytica

SUBMITTER: Lu J 

PROVIDER: S-EPMC12319046 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature