Caspofungin versus anidulafungin in patients with invasive candidiasis: a retrospective study with propensity-score-matched analysis.

ABSTRACT:

Background

Echinocandins are recommended as an initial treatment for invasive candidiasis. Although safety and efficacy profiles of both anidulafungin and caspofungin are well established, direct head-to-head comparisons have not been reported before.

Objective

Compare efficacy and safety of anidulafungin versus caspofungin among patients with invasive candidiasis.

Design

Retrospective observational study.

Methods

Adult patients with invasive candidiasis who were treated with either anidulafungin or caspofungin for ⩾5 days were retrospectively reviewed over a period of 6 years. The primary endpoint was global response, defined as clinical and microbiological success at the end of treatment duration.

Results

A total of 223 patients who received either ani

SUBMITTER: Elajez RH 

PROVIDER: S-EPMC12319202 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature