A Role for the Plastidial GPT2 Translocator in the Modulation of Lignin Biosynthesis.

ABSTRACT: Engineering plants with reduced lignin content can result in pleiotropic growth defects. In stems of Arabidopsis plants with reduced expression of hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase (HCT), the plastidial glucose 6-phosphate: phosphate co-transporter GPT2 is highly overexpressed, and this coincides with reduced lignin levels and extensive transcriptional and metabolic reprogramming. To explore the potential relationship between GPT2 expression and lignin accumulation, GPT2 transcript levels were evaluated in a suite of Arabidopsis thaliana and Medicago truncatula lignin-defective lines. We also examined lignin levels and composition, and transcriptomic and metabolic profiles in GPT2 loss-of-function, GPT2 overexpression, and wild-type Arabidopsis plants. Loss of GP

SUBMITTER: Raju AS 

PROVIDER: S-EPMC12319268 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature