Combination of imaging features on pancreatic CT for predicting early recurrence after upfront pancreatoduodenectomy of pancreatic ductal adenocarcinoma.

ABSTRACT:

Purpose

This study aimed to identify preoperative computed tomography (CT) imaging features for predicting early recurrence after upfront pancreatoduodenectomy of pancreatic ductal adenocarcinoma (PDAC), and to assess the diagnostic performance and prognostic relevance of their combination.

Methods

This study retrospectively included PDAC patients who underwent pancreatoduodenectomy and preoperative pancreatic CT between January 2016 and December 2023. Early recurrence is defined based on imaging evidence or pathology within 12 months after surgery. Significant imaging features for early recurrence were identified using univariate and multivariate analyses. Disease-free survival (DFS) and overall survival (OS) were analyzed in relation to these significant imaging features.<

SUBMITTER: Zhang S 

PROVIDER: S-EPMC12319333 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature