Carbonylation of hair proteins: A robust biomarker of molecular and structural oxidative damage in hair fibres.

ABSTRACT:

Objective

The first objective of this study is to compare two molecular markers, cysteic acid and protein carbonylation, to track the level of chemical oxidation and photochemical (UV) oxidation of human hair. The second objective is to investigate how the protein carbonylation biomarker evolution is associated with physical characteristics of the fibre. The third objective is to understand the damage localization within the hair sub-structure.

Materials and methods

For the chemical oxidation study European natural hair 6/0 (medium brown) is treated with non-pigmented commercial hair colour mixture and hair bleaching in increasing chemical oxidation conditions. For the photochemical study two European natural hair colours, 4/0 (dark brown) and 9/0 (extra light blond) are gra

SUBMITTER: Grosjacques C 

PROVIDER: S-EPMC12319463 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature