Left ventricular septal pacing combined with left ventricular pacing improves acute electric resynchronization, hemodynamic responses and clinical outcomes: results of SPORT study.

ABSTRACT:

Aims

Left bundle branch pacing is effective for cardiac resynchronization therapy (CRT), but the role of left ventricular septal pacing (LVSP) for CRT remains controversial due to lack of LBB capture. We hypothesized that combining LVSP with LV pacing (LVP) may provide additional benefits.

Methods and results

This prospective observational study enrolled consecutive patients undergoing LVSP for CRT. LVSP was acceptable if paced QRS duration (QRSd)＜130 ms or QRSd reduction ≥ 20%. If neither criterion were met, a CS-LV lead was implanted. Acute hemodynamic response (AHR) represented by LV maximum first derivative (dP/dtmax) was accessed. All patients were followed up for echocardiographic parameters, NT-proBNP levels, NYHA classes, and clinical events. The clinical outcomes in

SUBMITTER: Xue S 

PROVIDER: S-EPMC12319671 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature