Exploring neuroendocrine influences on the sensorimotor-association axis in a female and a male individual.

ABSTRACT: Human neuroimaging studies consistently show multimodal patterns of variabilityalong a key principle of macroscale cortical organization-thesensorimotor-association (S-A) axis. However, little is known about day-to-dayfluctuations in functional activity along this axis within an individual,including sex-specific neuroendocrine factors contributing to such transientchanges. We leveraged data from two densely sampled healthy young adults, onefemale and one male, to investigate intra-individual daily variability along theS-A axis, which we computed as our measure of functional cortical organizationby reducing the dimensionality of functional connectivity matrices. Dailyvariability was greatest in temporal limbic and ventral prefrontal regions inboth participants, and was more strongly pronoun

SUBMITTER: Serio B 

PROVIDER: S-EPMC12319837 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature