Evidence for a compensatory relationship between left- and right-lateralized brain networks.

ABSTRACT: The two hemispheres of the human brain are functionally asymmetric. At the network level, the language network exhibits left-hemisphere lateralization. While this asymmetry is widely replicated, the extent to which other functional networks demonstrate lateralization remains a subject of investigation. Additionally, it is unknown how the lateralization of one functional network may affect the lateralization of other networks within individuals. We quantified lateralization for each of 17 networks by computing the relative surface area on the left and right cerebral hemispheres. After examining the ecological, convergent, and external validity and test-retest reliability of this surface area-based measure of lateralization, we addressed two hypotheses across multiple datasets (Human Connect

SUBMITTER: Peterson M 

PROVIDER: S-EPMC12319987 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature