Pulsed-Field Ablation Versus Radiofrequency Ablation for Paroxysmal Atrial Fibrillation: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Pulsed-field ablation (PFA) is a nonthermal alternative to radiofrequency ablation (RFA) for patients with atrial fibrillation (AF). However, the role of PFA compared to RFA in patients with paroxysmal AF (PAF) remains unclear.

Objective

To compare the efficacy and safety of PFA and RFA in adult patients with PAF.

Methods

A systematic review and meta-analysis were conducted following the Cochrane methodology and reported in accordance with PRISMA guidelines. The PubMed, Embase, and Cochrane databases were searched through February 2025 for studies comparing PFA and RFA in adults with PAF. The outcomes of interest included procedure time, 1-year success rate, and major complications. All the statistical analyses were performed via R version 4.5 with a random

SUBMITTER: Martins Esteves I 

PROVIDER: S-EPMC12320123 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature