Prophylactic Effect of Prefrontal Alternating Current Stimulation on Postoperative Sleep Disturbance in Patients Undergoing Gynecological Laparoscope: A Randomized, Double-Blind, Sham-Controlled Trial.

ABSTRACT:

Aims

Postoperative sleep disturbance (PSD) is a common complication following surgical procedures. We aimed to evaluate the effect of prefrontal transcranial alternating current stimulation (tACS) in preventing PSD among patients undergoing gynecological laparoscopic surgery.

Methods

A total of 176 eligible patients, aged 18-65 years, with ASA Class I to III, and scheduled for gynecological laparoscopic surgery, were randomly allocated to receive either a single 20-min session of prefrontal tACS (2 mA, 7 Hz) or sham stimulation immediately after extubation. The primary outcome was the occurrence of PSD on postoperative day (POD) 1.

Results

The intention-to-treat analysis showed a statistically significant reduction in PSD incidence on POD 1 in the active tACS group (2

SUBMITTER: Du N 

PROVIDER: S-EPMC12320130 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature