Incidence, characteristics, and survival in early- and late-onset colorectal cancer.

ABSTRACT:

Background and purpose

To study incidence changes, tumor characteristics, and relative survival (RS) among patients with early- (18-49 years) and late-onset (≥50 years) colorectal cancer (CRC). Patient/material and methods: In this retrospective registry study, all patients diagnosed with CRC in Finland between 1991 and 2015 were included and followed until death or the end of 2022. Data were extracted from the Finnish Cancer Registry. Changes in incidence as an average annual percentage change as well as age- and sex-standardized RS for CRC were estimated for 5-year periods between 1991-1995 and 2011-2015.

Results

The annual increase in incidence was higher for early-onset CRC versus late-onset CRC (1.2% vs. 0.44%), primarily due to an increase in left-sided colon cancer (2

SUBMITTER: Hukkinen T 

PROVIDER: S-EPMC12320144 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature