Long-Term Nonprogression Is a Form of Response to Cardiac Resynchronization Therapy.

ABSTRACT:

Background

Cardiac resynchronization therapy (CRT) reduces morbidity and mortality in selected heart failure patients. A distinct subpopulation (so-called "nonprogressors") of patients shows neither amelioration nor worsening of echocardiographic parameters after CRT implantation.

Objectives

The authors sought to investigate the long-term outcomes and prognosis of a distinct subpopulation of heart failure patients termed "nonprogressors," after CRT implantation.

Methods

Retrospective single-center cohort analysis of 391 patients after CRT implantation. Based on echocardiography, patients were categorized into "super-responders" (Δ left ventricular ejection fraction [LVEF] >15% compared to baseline), "responders" (ΔLVEF >5% compared to baseline), "nonprogressors" (ΔLVE

SUBMITTER: Trenson S 

PROVIDER: S-EPMC12320150 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature