Impact of hereditary angioedema attacks on health-related quality of life and work productivity.

ABSTRACT:

Background

Hereditary angioedema (HAE) negatively impacts health-related quality of life (HRQoL). Few studies have characterized impairments to HRQoL, work productivity, and well-being during and following HAE attacks.

Methods

Patients with ≥1 HAE attack in the previous 3 months were recruited by the United States (US) HAE Association (HAEA) to complete an online survey. Respondents were categorized into those who did (Treated Cohort) and did not (Untreated Cohort) manage their last attack with on-demand treatment (OD). Adapted versions of the EuroQol-Five Dimensions-Five Levels (EQ-5D-5L), EuroQol Visual Analogue Scale (EQ VAS), and Work Productivity and Activity Impairment-General Health assessments were used.

Results

Attacks negatively impacted HRQoL and social and

SUBMITTER: O'Connor M 

PROVIDER: S-EPMC12320545 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature