Obstructive Coronary Artery Disease Improved Prediction by the COME-CCT Pretest Probability Calculator With Cardiac CT.

ABSTRACT:

Background

Combining pretest probability (PTP) with computed tomography angiography (CTA) for diagnosing obstructive coronary artery disease (CAD) has not yet been determined.

Objectives

The purpose of this study was to evaluate the accuracy of PTP calculation alone and with CTA for diagnosing CAD.

Methods

A total of 65 prospective diagnostic accuracy studies of patients clinically referred to invasive coronary angiography with stable chest pain were included in this international collaborative individual patient data Collaborative Meta-Analysis of Cardiac CT (COME-CCT) meta-analysis. Mixed-effects logistic regression with a data set-specific random intercept for clustering was applied to 4 models: the traditional Diamond-Forrester models, a PTP model based on the COM

SUBMITTER: Wieske V 

PROVIDER: S-EPMC12320659 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature