Electroconductivity of Saliva as a Diagnostic Tool for Dry Eye Disease: A Case-Control Study.

ABSTRACT:

Purpose

To evaluate the diagnostic potential of body fluid electroconductivity for dry eye disease (DED) and compare its accuracy with commonly used DED tests.

Methods

Individuals with dry eye (n = 36) and controls (n = 26) were enrolled in this case-control prospective study. Electroconductivity measurements were performed on blood, serum, tears, urine, and saliva. Dry eye assessments included tear film breakup time (TBUT) and Schirmer test (Schirmer), with symptoms evaluated using the Ocular Surface Disease Index (OSDI). Blood and urine analyses were performed to assess the baseline systemic profiles of both groups.

Results

Among all body fluids, saliva (saliva electroconductivity [ESaliva]) showed the most significant differences in electroconductivity between cont

SUBMITTER: Chen YK 

PROVIDER: S-EPMC12320899 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature