Gestational glyphosate exposure and early childhood neurodevelopment in a Puerto Rico birth cohort.

ABSTRACT:

Introduction

N-(phosphonomethyl)glycine, or glyphosate, is a non-selective systemic herbicide widely used in agricultural, industrial, and residential settings since 1974. Glyphosate exposure has been inconsistently linked to neurotoxicity in animals, and studies of effects of gestational exposure among humans are scarce. In this study we investigated relationships between prenatal urinary glyphosate analytes and early childhood neurodevelopment.

Methods

Mother-child pairs from the PROTECT-CRECE birth cohort in Puerto Rico with measures for both maternal urinary glyphosate analytes and child neurodevelopment were included for analysis (n = 143). Spot urine samples were collected 1-3 times throughout pregnancy and analyzed for glyphosate and aminomethylphosphonic acid (AMPA),

SUBMITTER: Jenkins HM 

PROVIDER: S-EPMC12321046 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature